ascl4+ lewis structure
ACSL4. The purpose of our studies was to determine the in vivo role of . HUGO Gene Nomenclature Committee (HGNC) approved gene symbol report Diseases associated with ACSL4 include Intellectual Developmental Disorder, X-Linked 63 and Stroke, Ischemic . Our ASCL4 polyclonal antibodies are developed in Rabbit. The gene view histogram is a graphical view of mutations across ASCL4. Explain why AsCl4+ has a bond angle of 109.5 There are four bonding pairs around As (tetrahedral structure) and all the bonding pairs repel equally 9 Suggest why graphene is an excellent conductor of electricity Plasmids containing this gene, or a homologous gene. Arsenic Chloride. Synonyms. The electron geometry of a water molecule is even though the molecular geometry is bent Learn more I agree I agree This antibody reacts with Human samples. Please help us improve further take a moment to fill our brief user survey. Distributors Login. ASCL4-201 ENSP00000345420 ENST00000342331: Q6XD76 [Direct mapping] Achaete-scute homolog 4 . Septic renal injury was significantly attenuated by the ferroptosis inhibitor Fer-1 in HFD-challenged mice. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free . Auto Crash SOS will send a message automatically to a 24/7 Emergency Response call center if the device detects a severe Validated for WB. CarLink ASCL4 module (with OBDII connector) 25" CCRSHAR harness (right-angled 2.5mm sub mini plug on one end and 4 multi-pin plugs on other end) HWAS406B harness adapter (4-pin male-to-4-pin female plugs) Quick Reference Dealer Install Guide; CarLink User Quick Reference Guide; CCRSHR diagram ASCL4 (Achaete-Scute Family BHLH Transcription Factor 4) is a Protein Coding gene. For immediate use, short term storage at 4C up . Lung ischemia-reperfusion (IR) injury is a common clinical pathology associated with high mortality. [supplied by OMIM, Mar 2008] Expression. Gene Effect. Ascl4 [d] Ascl4 [d] Expressed in. Show all. Human ASCL4. HGNC Approved Gene Symbol: ASCL4. Ascl4. Chemical Modification: DNA/RNA: Length: 20-80 nt: Affinity (Kd) 1nM~1M: Binding Conditions/Buffer: PBS; buffer system with Serum; other Mechanistically, ACSL4 enriched cellular membranes with long polyunsaturated 6 fatty acids. Ferroptosis, a novel mode of cell death elicited by iron-dependent phospholipid peroxidation, has been implicated in ischemic events. ASCL4 (acyl-CoA synthetase 4) - Elevated expression associated with claudin-low and basal-like BC phenotypes; may boost arachidonic acid metabolism through PTGS2, ALOX5, and AKT/mTOR pathways Figure 1. Color images are available online. . shRNA sequences correspond to ASCL4 siRNA Gene Silencer sequences After transduction, stable cell lines expressing the shRNA may be isolated via selection with puromycin Biosafety - Lentiviral Particles are replication-incompetent and are designed to self-inactivate after transduction and integration of shRNA constructs into genomic DNA of . Objective. HPA036116. Tng hp y v chi tit nht cn bng phng trnh iu ch t AsCl4 (Tetracloroasenat (III)) ra HCOOH (Axit formic) . The efficiency of the activation can . Target. For immediate use, short term storage at 4C up . Discovered in the 1970s, the tumor suppressor protein p53 (TP53) plays a critical role in the cellular response to various stresses, including DNA damage, hypoxia, nutrition starvation, and oncogene activation .Activation of p53 can lead to survival or death, depending on the levels of stress .Low levels of stress or damage trigger p53 activation to induce cell cycle arrest, DNA repair, and . (c) As the 4 Cl ions, which are weak-field ligands, approach the Au3+ ion in preparation for bonding, the 5d . Tng hp phng trnh c [AsCl4] [AsF6] (Tetrachloroarsen hexafluoroarsenate) l cht tham gia. Click the + buttons to view associations for . ASCL4 antibody LS-C749441 is an unconjugated rabbit polyclonal antibody to human ASCL4. Human ASCL4 (121549), Mouse Ascl4 (67341), Rat Ascl4 (299687), chicken ASCL4 (427912), dog ASCL4 (610742), cow ASCL4 (540730) Summary: Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265. FIG. 5. Acyl-CoA synthetase long-chain family member 4 (ACSL4) is one of Quick Order. Moderate to strong nucleolar and/or cytoplasmic positivity was observed in hepatocellular cancer as well as in several cases of malignant melanoma, urothelial, colorectal, ovarian and endometrial cancers. Organism. Cng n Thi & Bi Tp . Regulation of fatty acid (FA) metabolism is central to adipocyte dysfunction during diet-induced obesity (DIO). ASCL4 ( 1 gene ) Coverage: 99% at 20x. ASCL4. K09067 ASCL; achaete-scute complex protein. Chemical Engineering questions and answers. Of particular interest, it was observed that mismatch repair was enriched in CELSR3 and ASCL4 (shown in Fig. Answer to: What is the hybridization of AsCl4-? Pharmacological targeting of ACSL4 with thiazolidinediones, a class of antidiabetic compound, ameliorated . Xem tt c phng trnh [AsCl 4 ] [AsF 6] tham gia phn ng. Antibody staining with HPA036116 in immunohistochemistry. . These mutations are displayed at the amino acid level across the full length of the gene by default. Curated assertions on the My Cancer Genome website are housed within a Knowledge Management System (KMS) created through a partnership with GenomOncology that serves as a warehouse of biomarker, disease, and drug ontologies; biomarker-driven cancer clinical trials; therapeutic, prognostic, and diagnostic assertions; and unstructured . ASCL4 ( 1 gene ) Coverage: 99% at 20x. Rattus norvegicus (Rat) Status. Addgene Alerts Receive email alerts when new plasmids with this gene become available. AuCl 4. ASCL4, a basic helix-loop-helix transcription factor, is essential for the determination of cell fate and the development and differentiation of numerous tissues. Ascl4. DNA replication was differentially enriched in the ASCL4 high expression phenotype. In this infographic you will see the following information for ASCL4: database IDs, super-family, protein function, synonyms, molecular weight, chromosomal locations, tissues of expression, subcellular locations, post translational modifications, and related diseases . Browse primary antibodies for WB, Flow, IHC, ICC/IF, ELISA, IP, and other applications. We use cookies to ensure you get the best experience on our website. Antibodies with Advanced . Log in to subscribe to Addgene Alerts. ASCL4 | Achaete-scute-like protein 4 | Achaete-scute complex-like 4 | Achaete-scute homolog 4 | ASH-4 | BHLHa44 | Class II bHLH protein ASCL4 | HASH4. Gene Ontology (GO) annotations related to this gene include protein dimerization activity. Function i GO - Molecular function i. DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO . As. Receive our newsletter To keep up to date with the latest developments to our search engine, news from our market data analysis and improvements to our citation provision. Research Areas. An important paralog of this gene is ASCL5. 92 Validated Applications: IHC, IHC-P. Validated Species: Human. HGNC Approved Gene Symbol: ASCL4. Diseases associated with ACSL4 include Intellectual Developmental Disorder, X-Linked 63 and Stroke, Ischemic . Description achaete-scute family bHLH transcription factor 4 Also known as HASH4, bHLHa44 Species Homo sapiens Entrez ID 121549. Gene Ontology (GO) annotations related to this gene include protein dimerization activity . Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]). 12 ASCL4 Silencer Select Pre-designed, Validated, and Custom siRNA in Standard, HPLC, and In-vivo Ready Purities. See complete history. Description. Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of . 1 CRISPRa scramble vector, SKU GE100077. Disease. View Rabbit Polyclonal anti-ASCL4 Antibody (NBP1-90762). A majority of malignant cells were weakly stained or negative. Concentration. It could be a transcriptional regulator involved in skin development.Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and . BackgroundIschemic stroke is the main cause of disability worldwide, leading to a serious socioeconomic burden. Gene ID: 121549, updated on 25-Jan-2022. Function i GO - Molecular function i. DNA-binding transcription factor activity, RNA polymerase II-specific Source: GO . Long-chain acyl-CoA synthetase-4 (ACSL4) has been hypothesized to modulate the metabolic fates of polyunsaturated FA (PUFA), including arachidonic acid (AA), but the in vivo actions of ACSL4 are unknown. Acyl-CoA synthetase long-chain family member 4 (ACSL4) is considered a target of ferroptosis, but its specific role in ischemic stroke remains unclear. Phenotype data for mouse gene Ascl4. Lyophilized powder. H00916. Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]). Tested in Western Blot (WB) applications. Sample size available. Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]). Overview; Perturbation Effects; Characterization; Description; Dependent Cell Lines . Cytogenetic location: 12q23.3 Genomic coordinates (GRCh38): 12:107,774,703-107,776,643 (from NCBI) TEXT. (a) The electron configuration of Au is [Xe] 6s14f145d10. COVID-19. Safety. Emergency Roadside Assistance will come to you and assist you 24/7 for many roadside events like flat tire, out of gas, or towing. Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. Cart . Login. Product General Protocols . 2018 Nov 12. pii: S2405-4712(18)30433-2. doi: 10.1016/j.cels.2018.10.008. The bHLH domain of the putative HASH4 protein shows most identity to HASH3/ASCL3. We report the identification and cloning of a new, fourth member in the achaete-scute complex family of genes, Hash4 or Ascl4, which maps to chromosome 12q24.1. Review with no image -- $10/7/6/$10 CAD/70 Yuan/1110 Yen; Review with an image -- $25/18/15/$25 CAD/150 Yuan/2500 Yen; Submit a Review. Mus musculus (Mouse) Status. ASCL4. Plasmids containing this gene, or a homologous gene. RNAi (Achilles+DRIVE+Marcotte, DEMETER2): 0/710. ASCL4 has 1,199 functional associations with biological entities spanning 8 categories (molecular profile, organism, functional term, phrase or reference, disease, phenotype or trait, chemical, structural feature, cell line, cell type or tissue, gene, protein or microRNA) extracted from 38 datasets. y trng thi, mu sc cht v tnh s mol trong phn ng ha hc. Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of numerous tissues (Jonsson et al., 2004 [PubMed 15475265]). Voxx CarLink ASCL4 owner's manual. Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and the development and differentiation of . Determine the correct point group for . Plasmid EF1a_ASCL4_P2A_Hygro_Barcode from Dr. Prashant Mali's lab contains the insert ASCL4 and is published in Cell Syst. Diseases associated with ASCL4 include Secondary Hypertrophic Osteoarthropathy and Porokeratosis. Figure 1. For the second year you can renew the basic plan (without GPS) for $29.99, or with GPS for $79.99. Achaete-scute family bHLH transcription factor 4 . Contact Us. PCRP-ASCL4-2G8 was deposited to the DSHB by Common Fund - Protein Capture Reagents Program (DSHB Hybridoma Product PCRP-ASCL4-2G8) Storage and Handling Recommendations. There are no reviews for ASCL4 Antibody (NBP2-92741). Form. KEGG Orthology (KO) [BR: ko00001] 09180 Brite Hierarchies. Restrict the view to a region of the gene by dragging across the histogram to highlight the region of interest, or by using the sliders in the filters panel to the left. check them out. Choose from 1 of 3 ASCL4 antibodies, which have been validated in experiments with 6 images featured in our data gallery. This analysis is performed by Next Generation Sequencing (NGS) and is designed to . Schematic of data sources for My Cancer Genome. Product information: ASCL4 Antibody - Gentaur.com - Product info Furthermore, ferroptosis accumulation and related protein expression (ASCL4, FTH1, and GPX4) were altered by LPS stimulation in HFD-challenged mice and suppressed by NADPH oxidase inhibition via Vas2870 in vivo . Long-chain-fatty-acidCoA ligase 4 is an enzyme that in humans is encoded by the ACSL4 gene. [Polyclonal ASCL4; Anti-ASCL4; ASCL 4; HASH4; achaete-scute complex homolog 4; Drosophila; ASCL-4; ASCL4] Products_gene_name [ASCL4] Clonality. It is reactive with human and chimpanzee. This analysis is performed by Next Generation Sequencing (NGS) and is designed to . An important paralog of this gene is ASCL5. Schematic of data sources for My Cancer Genome. Polyclonal. Although many cell products are maintained at 4C for years without loss of activity, shelf-life at 4C is highly variable. It could be a transcriptional regulator involved in skin development.Basic helix-loop-helix transcription factors, such as ASCL4, are essential for the determination of cell fate and . Products. Validated for WB. Moreover, ACSL4 was preferentially expressed in a panel of basal-like breast cancer cell lines and predicted their sensitivity to ferroptosis. Invitrogen Anti-ASCL4 Polyclonal, Catalog # PA5-43650. GSEA, gene set enrichment analysis. Congenital central hypoventilation syndrome. SANTA CRUZ BIOTECHNOLOGY, INC. ACSL4 (A-5): sc-271800 Santa Cruz Biotechnology, Inc. 1.800.457.3801 831.457.3800 fax 831.457.3801 Europe +00800 4573 8000 49 6221 4503 0 www.scbt.com BACKGROUND Acyl-CoA synthetases, also known as long-chain fatty-acid CoA synthases This plasmid is available through Addgene. Curated assertions on the My Cancer Genome website are housed within a Knowledge Management System (KMS) created through a partnership with GenomOncology that serves as a warehouse of biomarker, disease, and drug ontologies; biomarker-driven cancer clinical trials; therapeutic, prognostic, and diagnostic assertions; and unstructured . CRISPR (DepMap 22Q1 Public+Score, Chronos): 3/1070. Features (continued) Within the first year of service, you can upgrade to GPS from the included base service plan for $50.00. Description. GA114755G3, ASCL4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa. Description achaete-scute family bHLH transcription factor 4 Also known as HASH4, bHLHa44 Species Homo sapiens Entrez ID 121549. Expression of ASCL4 (bHLHa44, HASH4) in kidney tissue. In addition to tracking, the system lets you set up to three Geo-Fence locations and a Security Fence feature. Organism. Supplied as 100 L purified antibody (0.5 mg/mL). 09182 Protein families: genetic information processing. ASCL4 antibody LS-C454355 is an FITC-conjugated rabbit polyclonal antibody to ASCL4 (N-Terminus) from human. Among its related pathways are arachidonate biosynthesis III (6-desaturase, mammals) and Arachidonic acid metabolism . Go to complete Gene record for ASCL4; Go to Variation Viewer for ASCL4 variants; Summary. Identify and locate the symmetry elements in the species a) to l) whose Lewis structures and geometric structures you determined in problem 1. In this study, we investigate . By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount. ASCL4 achaete-scute family bHLH transcription factor 4. Arsenic chloride is formed when Arsenic combines with three Chlorine atoms as Arsenic contains three valence electrons. ACSL4 (Acyl-CoA Synthetase Long Chain Family Member 4) is a Protein Coding gene. Predicted intracellular proteins Intracellular proteins predicted by MDM and MDSEC Transcription factors Basic domains Mapped to neXtProt neXtProt - Evidence at protein level. Ferroptosis is a non-apoptotic form of programmed cell death and is related to various diseases. Final antibody concentration is 1 mg/ml in PBS buffer. Find the ASCL4 antibody that fits your needs. Predict the shape, state the hybridization of the central atom, and give the ideal bond angle (s) and any expected deviations for AsCl4 Shape: trigonal pyramidal O tetrahedral O seesaw T-shaped sp"d" hybrid AO where: m= and n = Ideal bond angle (s): (Select one or more.) Image: Illustrated plasmid map in PNG format. In today's video, we help you determine the polarity of the Triiodide ion. Resources. Diseases associated with ASCL4 include Secondary Hypertrophic Osteoarthropathy and Porokeratosis . : Entry status i: Reviewed (UniProtKB . Data for gene Ascl4 is all freely available for download. HUMAN ACHAETE-SCUTE HOMOLOG 4; HASH4. Specimen Requirements: Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request) Test Limitations: All sequencing technologies have limitations. (b) The electron configuration of Au3+ is [Xe] 6s04f145d8. Enrichment plots of the five signature-related mRNAs from GSEA. We use cookies to enhance the usability of our website. 1 CRISPRa-Enhancer vector, SKU GE100056. Hi Guys!Welcome back to Geometry of Molecules where we make chemistry more fun! PCRP-ASCL4-2G8 was deposited to the DSHB by Common Fund - Protein Capture Reagents Program (DSHB Hybridoma Product PCRP-ASCL4-2G8) Storage and Handling Recommendations. HUMAN ACHAETE-SCUTE HOMOLOG 4; HASH4. Bn c th click vo cc phng trnh ha hc sau tm xem cht [AsCl 4 ] [AsF 6] c th iu ch ra c nhng cht no. Specimen Requirements: Blood (two 4ml EDTA tubes, lavender top) or Extracted DNA (3ug in EB buffer) or Buccal Swab or Saliva (kits available upon request) Test Limitations: All sequencing technologies have limitations. Unreviewed-Annotation score: -Protein predicted i. For more info on ASCL4, check out the ASCL4 Infographic We have 30,000+ of these available, one for each gene! The expression of Hash4 and Hash3 was analyzed by reverse transcriptase polymerase chain reaction (PCR . The dx2y2 level is at such a high level that it remains unoccupied in almost all d8 complexes. 45 90 109.5 120 Deviations . 03000 Transcription factors. Entry name i: ASCL4_HUMAN: Accession i: Q6XD76 Primary (citable) accession number: Q6XD76 Secondary accession number(s): Q7RTS2: Entry history i: Integrated into UniProtKB/Swiss-Prot: : February 5, 2008: Last sequence update: : July 5, 2004: Last modified: : May 25, 2022: This is version 133 of the entry and version 1 of the sequence. ASCL4, a basic helix-loop-helix transcription factor, is essential for the determination of cell fate and the development and differentiation of numerous tissues. The protein encoded by this gene is an isozyme of the long-chain fatty-acid - coenzyme A ligase family. Unreviewed-Annotation score: -Protein predicted i. Cytogenetic location: 12q23.3 Genomic coordinates (GRCh38): 12:107,774,703-107,776,643 (from NCBI) TEXT. Among its related pathways are arachidonate biosynthesis III (6-desaturase, mammals) and Arachidonic acid metabolism .
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